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Calcitonin gene‑related peptide enhances osteogenic differentiation and recruitment of bone marrow mesenchymal stem cells in rats

11 Jun 2019

Abstract excerpt

The present study evaluated the effects of calcitonin gene‑related peptide (CGRP) on bone marrow mesenchymal stem cells (BMMSCs) in vitro and in a rat model of mandibular distraction osteogenesis (MDO). Rat BMMSCs were isolated then treated with CGRP or CGRP antagonist (CGRP8‑37). The proliferation and migration ability of BMMSCs was determined using 5‑bromo‑2'‑deoxyuridine and Transwell assays, respectively....

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PMID: 31316600
DOI: 10.3892/etm.2019.7659

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