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Transcriptional analysis of the divergent <i>cagAB</i> genes encoded by the pathogenicity island of <i>Helicobacter pylori</i>

1 Oct 1997

Abstract excerpt

Helicobacter pylori strains isolated from most patients with peptic ulcer disease and adenocarcinoma express the vacuolating toxin VacA and contain a pathogenicity island named cag. The cag pathogenicity island codes for more than 40 putative proteins with features similar to bacterial secretion systems. One of these proteins, CagA, is an immunodominant antigen with unknown function encoded by the cagA gene. In...

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PMID: 9383160
DOI: 10.1046/j.1365-2958.1997.5831949.x

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