Article
Imprinting mutations on human chromosome 15.
Human mutation - 1 Jan 1997
Horsthemke B, Dittrich B, Buiting K
Abstract excerpt
Genomic imprinting is an epigenetic process by which the male and the female germline of viviparous taxa confer a sex-specific mark (imprint) on certain chromosomal regions. The imprint is reset in the germline of each generation, inherited through somatic cell divisions during postzygotic development and used to regulate parent-of-origin specific expression of susceptible genes. Aberrant imprinting leading to...
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