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Article

Cytotoxic and mutagenic effects of chronic low-dose-rate irradiation on TERT-immortalized human cells.

Radiation research - 1 Mar 2005

Nakamura Hideaki, Fukami Hiroko, Hayashi Yuko, Tachibana Akira, Nakatsugawa Shigekazu, Hamaguchi Michinari, Ishizaki Kanji

Abstract excerpt

To analyze the genetic effects of low-dose-rate radiation on human cells, we used human telomere reverse transcriptase (TERT)-immortalized fibroblast cells obtained from normal individuals. We studied the effect of low-dose-rate (0.3 mGy/ min) and high-dose-rate (2 Gy/min) radiation on cells in a confluent state. Survival and micronucleus induction frequency showed higher resistance after irradiation at low dose...

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Source

Identifiers

PMID: 15733035
DOI: 10.1667/rr3310

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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