Article
Lysis of human alveolar macrophages by lymphokine-activated killer cells.
Chest - 1 Jun 1990
Maruyama M, Kawasaki A, Suzuki H, Yamashita N, Yano S
Abstract excerpt
In order to determine if human LAK cells were cytotoxic against autologous AM phi, we studied the ability of human peripheral blood MNCs, stimulated in vitro with recombinant human IL-2, to lyse AM phi in a four-hour 51Cr-release assay. These cells showed significant cytotoxicity against autologo...
Topics
- Bronchoalveolar Lavage Fluid
- Cells, Cultured
- Cytotoxicity, Immunologic
- Female
- Humans
- In Vitro Techniques
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Leukocytes, Mononuclear
- Macrophages
- Male
- Middle Aged
- Phenotype
- Pulmonary Alveoli
- Recombinant Proteins
- Time Factors
