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Article

Study of the thrombopoitin receptor in essential thrombocythemia.

Leukemia - 1 Nov 1997

Kiladjian J J, Elkassar N, Hetet G, Briere J, Grandchamp B, Gardin C

Abstract excerpt

Essential thrombocythemia (ET) is a myeloproliferative disorder associated with megakaryocytic hyperplasia and thrombocytosis. In this disease, in vitro autonomous growth of megakaryocytic colonies has been demonstrated by various investigators. This phenomenon is impaired by the inhibition of the thrombopoietin/c-mpl pathway. In order to evaluate the potential role of mutations of the receptor gene in the origin...

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PMID: 9369413
DOI: 10.1038/sj.leu.2400845

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Study of the thrombopoitin receptor in essential thrombocythemia.PMID 9369413Read ↗

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