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Article

Identification of residues critical for the human coronavirus 229E receptor function of human aminopeptidase N.

1 Nov 1997

Abstract excerpt

Aminopeptidase N (APN) is the major cell surface receptor for group 1 coronaviruses. In this study, we have isolated and characterized a feline APN cDNA and shown that the transfection of human embryonic kidney cells with this cDNA renders them susceptible to infection with the feline coronavirus feline infectious peritonitis virus, the human coronavirus (HCV) 229E and the porcine coronavirus porcine...

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PMID: 9367365
DOI: 10.1099/0022-1317-78-11-2795

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