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Article

The expression of key cell cycle markers and presence of human papillomavirus in squamous cell carcinoma of the tonsil

18 Nov 2003

Abstract excerpt

BACKGROUND: Chemical carcinogens induce squamous cell carcinoma (SCC) of the head and neck by targeting the p53 and the retinoblastoma (pRb) pathways. Human papillomavirus (HPV) might have an etiologic role in these cancers at particular sites. Few studies have compared cell cycle protein expression in HPV-positive and HPV-negative tumors in this region. METHODS: Fifty tonsil SCCs were analyzed for HPV by PCR and...

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PMID: 14724900
DOI: 10.1002/hed.10335

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