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Article

End4p/Sla2p interacts with actin-associated proteins for endocytosis in Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Nov 1997

Wesp A, Hicke L, Palecek J, Lombardi R, Aust T, Munn A L, Riezman H

Abstract excerpt

end4-1 was isolated as a temperature-sensitive endocytosis mutant. We cloned and sequenced END4 and found that it is identical to SLA2/MOP2. This gene is required for growth at high temperature, viability in the absence of Abp1p, polarization of the cortical actin cytoskeleton, and endocytosis. We used a mutational analysis of END4 to correlate in vivo functions with regions of End4p and we found that two regions...

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Source

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Identifiers

PMID: 9362070
DOI: 10.1091/mbc.8.11.2291
PMCID: PMC25709

Genes

SLA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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