Article
Yeast actin cytoskeleton mutants accumulate a new class of Golgi-derived secretary vesicle.
Molecular biology of the cell - 1 Aug 1997
Mulholland J, Wesp A, Riezman H, Botstein D
Abstract excerpt
Many yeast actin cytoskeleton mutants accumulate large secretory vesicles and exhibit phenotypes consistent with defects in polarized growth. This, together with actin's polarized organization, has suggested a role for the actin cytoskeleton in the vectorial transport of late secretory vesicles to the plasma membrane. By using ultrastructural and biochemical analysis, we have characterized defects manifested by...
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