Article
The Sla2p talin domain plays a role in endocytosis in Saccharomyces cerevisiae.
Genetics - 1 Dec 2003
Baggett Jennifer J, D'Aquino Katharine E, Wendland Beverly
Abstract excerpt
Clathrin-binding adaptors play critical roles for endocytosis in multicellular organisms, but their roles in budding yeast have remained unclear. To address this question, we created a quadruple mutant yeast strain lacking the genes encoding the candidate clathrin adaptors Yap1801p, Yap1802p, and Ent2p and containing a truncated version of Ent1p, Ent1DeltaCBMp, missing its clathrin-binding motif. This strain was...
Topics
- Actins
- Adaptor Proteins, Signal Transducing
- Adaptor Proteins, Vesicular Transport
- Carrier Proteins
- Clathrin
- Coated Pits, Cell-Membrane
- Cytoskeletal Proteins
- Cytoskeleton
- Endocytosis
- Mutation
- Protein Binding
- Protein Structure, Tertiary
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins