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Article

Identification of a new 'TIGR' mutation in a family with juvenile-onset primary open angle glaucoma.

Ophthalmic genetics - 1 Sept 1997

Stoilova D, Child A, Brice G, Crick R P, Fleck B W, Sarfarazi M

Abstract excerpt

Positional mapping of families segregating for juvenile-onset primary open angle glaucoma (JOAG) has previously identified a locus (GLCIA) for this condition on the long arm of chromosome I. Recently, three mutations in the TIGR gene (Trabecular meshwork Inducible Gluco-corticoid Response protein) have been described in a total of ten familial, three sporadic, and one normal subject. One of the familial cases has...

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Identifiers

PMID: 9361308
DOI: 10.3109/13816819709057124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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