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Article

Molecular structure and evolution of an alpha satellite/non-alpha satellite junction at 16p11.

Human molecular genetics - 1 Jan 2000

Horvath J E, Viggiano L, Loftus B J, Adams M D, Archidiacono N, Rocchi M, Eichler E E

Abstract excerpt

We have determined the detailed molecular structure and evolution of an alpha satellite junction from human chromosome 16p11. The analysis reveals that the alpha satellite sequence bordering the transition lacks higher-order structure and that the non-alpha satellite portion consists of a mosaic of duplicated segments of complex evolutionary origin. The 16p11 junction was formed recently (5-10 million years ago)...

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PMID: 10587586
DOI: 10.1093/hmg/9.1.113

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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