Article
Role of the constriction loop in the gating of outer membrane porin PhoE of Escherichia coli.
FEBS letters - 6 Oct 1997
Eppens E F, Saint N, Van Gelder P, van Boxtel R, Tommassen J
Abstract excerpt
Porins form voltage-gated channels in the bacterial outer membrane. These proteins are composed of three identical subunits, each forming a 16-stranded beta-barrel. In this study, the role in voltage gating of a loop that forms a constriction within the pore was studied. The channel characteristics of mutant PhoE porins, in which the tip of the constriction loop was connected to the barrel wall, were determined....
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