Article
Spectrum of spontaneous and 2,4,6-trinitrotoluene (TNT)-induced mutations in Salmonella typhimurium strains with different nitroreductase and O-acetyltransferase activities.
Mutation research - 6 Oct 1997
Väätänen A K, Ridanpää M, Norppa H, Kociba P
Abstract excerpt
Spontaneous and 2,4,6-trinitrotoluene (TNT)-induced mutation spectra were determined at the hisD3052 allele of Salmonella typhimurium strains TA98, YG1021 (nitroreductase-overproducing) and YG1024 (O-acetyltransferase-overproducing). In TA98, 55% (11/20) of the spontaneous reversions and 95% (19/...
Topics
- Acetyltransferases
- Alcohol Oxidoreductases
- Bacterial Proteins
- Base Sequence
- DNA Mutational Analysis
- DNA, Bacterial
- Molecular Sequence Data
- Mutagenicity Tests
- Mutagens
- Mutation
- Nitroreductases