Article
Retroviral gene transfer: effects on endothelial cell phenotype.
The Journal of surgical research - 15 Jul 1998
Inaba M, Toninelli E, Vanmeter G, Bender J R, Conte M S
Abstract excerpt
BACKGROUND: Endothelial cells (EC) are an attractive target for somatic cell gene therapy, both for the treatment of cardiovascular disease and for the systemic delivery of recombinant gene products directly into the circulation. Recent evidence, however, suggests that viral transduction may indu...
Topics
- Cell Division
- Cells, Cultured
- E-Selectin
- Endothelium, Vascular
- Gene Transfer Techniques
- Histocompatibility Antigens Class II
- Humans
- Intercellular Adhesion Molecule-1
- Lac Operon
- Leukemia Virus, Murine
- Phenotype
- Transduction, Genetic