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Article

Necdin-deficient mice do not show lethality or the obesity and infertility of Prader-Willi syndrome

1 May 1999

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10319852
DOI: 10.1038/8722

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Related research

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Necdin-deficient mice do not show lethality or the obesity and infertility of Prader-Willi syndromePMID 10319852Read ↗

Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during developmentSemantic proximity Read ↗

Investigation of a Novel Mouse Model of Prader-Willi Syndrome with Invalidation of <i>Necdin</i> and <i>Magel2</i>Semantic proximity Read ↗

Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons.Semantic proximity Read ↗

NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expression.Semantic proximity Read ↗

Arx is required for normal enteroendocrine cell development in mice and humansSemantic proximity Read ↗

The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal regionSemantic proximity Read ↗

Systematic screening for mutations in the human necdin gene (NDN): identification of two naturally occurring polymorphisms and association analysis in body weight regulation.Semantic proximity Read ↗

Expression and imprinting of MAGEL2 suggest a role in Prader-willi syndrome and the homologous murine imprinting phenotype.Semantic proximity Read ↗

Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinerySemantic proximity Read ↗

A novel mutation in the nucleoporin NUP35 causes murine degenerative colonic smooth muscle myopathySemantic proximity Read ↗

Firing activity of locus coeruleus noradrenergic neurons decreases in necdin-deficient mice, an animal model of Prader–Willi syndromeSemantic proximity Read ↗

Similar phenotypes of Girdin germ-line and conditional knockout mice indicate a crucial role for Girdin in the nestin lineage.Semantic proximity Read ↗

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