Article
Fine mapping and characterization of candidate lung tumor resistance genes for the Par2 locus on mouse chromosome 18.
Experimental lung research - 1 Dec 2000
Zhang Z, Lin L, Liu G, Wang M, Hill J, Wang Y, You M, Devereux T R
Abstract excerpt
In a number of recent studies, a lung tumor resistance locus designated either Par2 or Pas7 was mapped to distal chromosome 18 in crosses between susceptible A/J and more resistant BALB/c mice. This locus is important in that it accounts for as much as 60% of the difference in lung tumor susceptibility between the A/J and BALB/c mice, both of which contain the susceptible allele of Kras2, a marker and strong...
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