Article
Hindshaker, a novel myelin mutant showing hypomyelination preferentially affecting the spinal cord.
Journal of neurocytology - 1 Aug 1997
King H, McCulloch M C, Barrie J A, Kyriakides E, Beechey C V, Cattanach B M, Griffiths I R
Abstract excerpt
Animals with spontaneous mutations affecting myelin formation have provided useful information about the genetic and cellular mechanisms regulating normal and abnormal myelination. In this paper we describe a novel murine mutation termed hindshaker (hsh), which is inherited in an autosomal recess...
Topics
- Animals
- Autoradiography
- Female
- Glial Fibrillary Acidic Protein
- Hindlimb
- Immunohistochemistry
- In Situ Hybridization
- Male
- Mice
- Mice, Inbred C3H
- Mice, Neurologic Mutants
- Mutation
- Myelin Basic Protein
- Myelin Proteolipid Protein
- Myelin Sheath
- Phenotype
- RNA, Messenger
- Spinal Cord