Article
Renal function and renotropic effects of secretin in cystic fibrosis.
European journal of medical research - 30 Oct 1997
Windstetter D, Schaefer F, Schärer K, Reiter K, Eife R, Harms H K, Bertele-Harms R, Fiedler F, Tsui L C, Reitmeir P, Horster M, Hadorn H B
Abstract excerpt
In ten cystic fibrosis patients and nine age-matched controls, renal function was determined before and after infusion of secretin. Under baseline conditions creatinine excretion and clearance were significantly elevated, exclusively due to those patients who were homozygous for the DF508 mutation (153 vs 132 ml/min*1.73m2), whereas the glomerular filtration rate, measured by inulin clearance showed no...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.