Article
Cystic fibrosis transmembrane conductance regulator (CFTR) and renal function.
Wiener klinische Wochenschrift - 27 Jun 1997
Stanton B A
Abstract excerpt
The cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel is expressed in all nephron segments. Although mutations in CFTR are not associated with major changes in renal function, drug excretion by the kidneys is altered in cystic fibrosis (CF) as is the ability of the kidneys to concentrate and dilute the urine and excrete a salt load. It is not clear if these changes in renal function are...
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