Cystic fibrosis transmembrane conductance regulator (CFTR) and renal function.

Article

Cystic fibrosis transmembrane conductance regulator (CFTR) and renal function.

Wiener klinische Wochenschrift - 27 Jun 1997

Stanton B A

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel is expressed in all nephron segments. Although mutations in CFTR are not associated with major changes in renal function, drug excretion by the kidneys is altered in cystic fibrosis (CF) as is the ability of the kidneys to...

Topics

Animals
Cells, Cultured
Chloride Channels
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Humans
Kidney
Mutation
Nephrons
Patch-Clamp Techniques
Polycystic Kidney Diseases
RNA, Messenger
Rabbits
Water-Electrolyte Balance

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