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Article

Development of a functional skin matrix requires deposition of collagen V heterotrimers.

Molecular and cellular biology - 1 Jul 2004

Chanut-Delalande Hélène, Bonod-Bidaud Christelle, Cogne Sylvain, Malbouyres Marilyne, Ramirez Francesco, Fichard Agnès, Ruggiero Florence

Abstract excerpt

Collagen V is a minor component of the heterotypic I/III/V collagen fibrils and the defective product in most cases of classical Ehlers Danlos syndrome (EDS). The present study was undertaken to elucidate the impact of collagen V mutations on skin development, the most severely affected EDS tissues, using mice harboring a targeted deletion of the alpha2(V) collagen gene (Col5a2). Contrary to the original report,...

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Identifiers

PMID: 15199158
DOI: 10.1128/MCB.24.13.6049-6057.2004
PMCID: PMC480903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Development of a functional skin matrix requires deposition of collagen V heterotrimers.PMID 15199158Read ↗

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