Article
Dissecting Wnt signalling pathways and Wnt-sensitive developmental processes through transient misexpression analyses in embryos of Xenopus laevis.
Development (Cambridge, England). Supplement - 1 Jan 1993
Moon R T, Christian J L, Campbell R M, McGrew L L, DeMarais A A, Torres M, Lai C J, Olson D J, Kelly G M
Abstract excerpt
We review evidence that Xenopus Wnts (Xwnts) have activities consistent with their hypothesized roles as secreted signalling factors involved in multiple developmental processes. Transient misexpression of different Xwnts has distinct effects upon early development, and upon the formation of tissues in UV-irradiated embryos. Misexpression of Xwnts also has distinct effects on the in vitro differentiation of...
Topics
- Animals
- Embryonic Induction
- Gene Expression
- Mesoderm
- Mutation
- Proto-Oncogene Proteins
- Signal Transduction
- Xenopus laevis