Evolutionary dynamics of genetic variation in Epstein-Barr virus isolates of diverse geographical origins: evidence for immune pressure-independent genetic drift.

doi:10.1128/JVI.71.11.8340-8346.1997

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Article

Evolutionary dynamics of genetic variation in Epstein-Barr virus isolates of diverse geographical origins: evidence for immune pressure-independent genetic drift.

Journal of virology - 1 Nov 1997

Khanna R, Slade R W, Poulsen L, Moss D J, Burrows S R, Nicholls J, Burrows J M

Abstract excerpt

The question whether immune pressure exerted by cytotoxic T lymphocytes (CTLs) can influence the long-term evolution of genetically stable viruses such as Epstein-Barr virus (EBV) has generated considerable scientific interest, primarily due to its important implications for the overall biology o...

Topics

Amino Acid Sequence
Biological Evolution
Cells, Cultured
DNA, Viral
Epitope Mapping
Gene Frequency
Genetic Variation
Geography
Herpesvirus 4, Human
Humans
Lymphocytes
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phylogeny

Polymorphism, Genetic

Sequence Alignment

Sequence Homology, Amino Acid

Sequence Homology, Nucleic Acid

T-Lymphocytes, Cytotoxic

Source

Open in PubMed Open full text

Identifiers

PMID: 9343187
DOI: 10.1128/JVI.71.11.8340-8346.1997
PMCID: PMC192293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9343187-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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