Article
HLA-A11 Epitope Loss Isolates of Epstein-Barr Virus From a Highly A11 <sup>+</sup> Population
2 Apr 1993
Abstract excerpt
Cytotoxic T lymphocytes (CTLs) control viral infections by recognizing viral peptides presented by major histocompatibility complex (MHC) class I molecules. Human leukocyte antigen (HLA)-A11-restricted CTLs that recognize peptide residues 416 to 424 of the Epstein-Barr virus (EBV) nuclear antigen-4 frequently dominate EBV-induced responses in A11+ Caucasian donors. This epitope is conserved in type A EBV strains...
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