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The Molecular Epidemiology and Evolution of Epstein‐Barr Virus: Sequence Variation and Genetic Recombination in the Latent Membrane Protein‐1 Gene

1 Apr 1999

Abstract excerpt

The phylogeny and evolution of Epstein-Barr virus (EBV) genetic variation are poorly understood. EBV latent membrane protein-1 (LMP-1) gene sequences are especially heterogeneous and may be useful as a tool for EBV genotype identification. Therefore, LMP-1 sequences obtained directly from EBV-infected human tissues were examined by PCR amplification and cloning. EBV genotypes were defined as "strains" from among...

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PMID: 10068570
DOI: 10.1086/314672

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