Article
Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium.
Biological psychiatry - 1 Feb 1997
Sander T, Harms H, Podschus J, Finckh U, Nickel B, Rolfs A, Rommelspacher H, Schmidt L G
Abstract excerpt
Hereditary factors confer susceptibility to alcohol dependence. Alcohol mediates its reinforcing effects by enhancing dopamine activity in the mesolimbic dopamine system. The role of the dopamine transporter in terminating dopaminergic activity in synaptic neurotransmission suggests that variants...
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