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Article

Screening of the C677T mutation on the methylenetetrahydrofolate reductase gene in French patients with neural tube defects.

Human genetics - 1 Oct 1997

Mornet E, Muller F, Lenvoisé-Furet A, Delezoide A L, Col J Y, Simon-Bouy B, Serre J L

Abstract excerpt

We report the analysis of the distribution of the C677T mutation on the methylenetetrahydrofolate reductase (MTHFR) gene in prenatally diagnosed neural tube defects (NTD) cases and controls. In contrast to previous reports, we found the same distribution in fetuses with NTD and controls, which suggests that the MTHFR C677T mutation cannot be regarded as a genetic risk factor for NTD.

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Source

Identifiers

PMID: 9341863
DOI: 10.1007/s004390050544

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Screening of the C677T mutation on the methylenetetrahydrofolate reductase gene in French patients with neural tube defects.PMID 9341863Read ↗

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