Article
[Beta thalassemia in Germany: molecular genetics and clinical phenotype in immigrant and in the native population].
Klinische Padiatrie - 1 Jan 2000
Schwarz C, Vetter B, Kohne E, Kulozik A E
Abstract excerpt
BACKGROUND: In Germany there are about 300-400 patients with homozygous beta-thalassaemia who immigrated from endemic regions mostly in the Mediterranean. In the non-immigrant population beta-thalassaemia is rare with only single case reports of homozygous patients. Heterozygous beta-thalassaemia, however, is more common and must be considered in the differential diagnosis of hypochromic anemia. PATIENTS AND...
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- DNA Mutational Analysis
- Diagnosis, Differential
- Emigration and Immigration
- Female
- Gene Frequency
- Genetic Carrier Screening
- Genetics, Population