Article
Translational repressor bruno plays multiple roles in development and is widely conserved.
Genes & development - 1 Oct 1997
Webster P J, Liang L, Berg C A, Lasko P, Macdonald P M
Abstract excerpt
oskar (osk) mRNA is tightly localized to the posterior pole of the Drosophila oocyte, where the subsequent expression of Osk protein directs abdomen and germ-line formation in the developing embryo. Misplaced expression of Osk protein leads to lethal body patterning defects. The Osk message is tr...
Topics
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- Conserved Sequence
- DEAD-box RNA Helicases
- Drosophila
- Drosophila Proteins
- Evolution, Molecular
- Female
- Gene Expression Regulation
- Genes, Insect
- Insect Proteins
- Male
- Molecular Sequence Data
- Mutation
- Oogenesis
- Phenotype
- Protein Biosynthesis