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Article

Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibition.

Antimicrobial agents and chemotherapy - 1 Dec 2001

Takei M, Fukuda H, Kishii R, Hosaka M

Abstract excerpt

The antibacterial activities and target inhibition of 15 quinolones against grlA and gyrA mutant strains were studied. The strains were obtained from wild-type Staphylococcus aureus MS5935 by selection with norfloxacin and nadifloxacin, respectively. The antibacterial activities of most quinolones against both mutant strains were lower than those against the wild-type strain. The ratios of MICs for the gyrA...

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Identifiers

PMID: 11709337
DOI: 10.1128/AAC.45.12.3544-3547.2001
PMCID: PMC90866

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