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Article

Role of embB in natural and acquired resistance to ethambutol in mycobacteria.

Antimicrobial agents and chemotherapy - 1 Oct 1997

Alcaide F, Pfyffer G E, Telenti A

Abstract excerpt

The mycobacterial embCAB operon encodes arabinosyl transferases, putative targets of the antimycobacterial agent ethambutol (EMB). Mutations in embB lead to resistance to EMB in Mycobacterium tuberculosis. The basis for natural, intrinsic resistance to EMB in nontuberculous mycobacteria (NTM) is not known; neither is the practical implication of resistance to EMB in the absence of embB mutations in M....

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Source

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Identifiers

PMID: 9333060
DOI: 10.1128/AAC.41.10.2270
PMCID: PMC164105

Genes

EMB
NTM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Role of embB in natural and acquired resistance to ethambutol in mycobacteria.PMID 9333060Read ↗

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A single point mutation in the embB gene is responsible for resistance to ethambutol in Mycobacterium smegmatis.Semantic proximity Read ↗

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Mutations within embCAB Are Associated with Variable Level of Ethambutol Resistance in Mycobacterium tuberculosis Isolates from China.Semantic proximity Read ↗

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