Article
Chromosome assignment of aberrant NotI restriction DNA fragments in primary hepatocellular carcinoma.
Gene - 15 Sept 1997
Yoshikawa H, Nagai H, Oh K S, Tamai S, Fujiyama A, Nakanishi T, Kajiyama G, Matsubara K
Abstract excerpt
DNA aberrations in human hepatocellular carcinoma (HCC) were studied by two-dimensional DNA electrophoresis analysis. Five intensified and 60 dwindling spots were detected recurrently in the two-dimensional profile which showed about 3000 restriction DNA fragments as distinctive spots. We assigned these aberrant spots to chromosomes, using the chromosome-assigned two-dimensional profile. Four of the five...
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