Article
Episodic evolution and turnover of HLA-B in the indigenous human populations of the Americas.
Tissue antigens - 1 Sept 1997
Parham P, Arnett K L, Adams E J, Little A M, Tees K, Barber L D, Marsh S G, Ohta T, Markow T, Petzl-Erler M L
Abstract excerpt
Nucleotide sequences were determined for the HLA-A, B and C alleles of three populations of Amerindians: the Havasupai tribe from North America, and the Guarani and Kaingang tribes from South America. All 15 Havasupai alleles are found in Eastern Hemisphere populations, whereas the Guarani and Ka...
Topics
- Alleles
- Cell Line
- Evolution, Molecular
- Genetic Variation
- HLA-A Antigens
- HLA-B Antigens
- HLA-C Antigens
- Histocompatibility Testing
- Humans
- Indians, North American
- Indians, South American
- Sequence Analysis, DNA