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Article

Dissimilar evolution of B-locus versus A-locus and class II loci of the HLA region in South American Indian tribes.

Tissue antigens - 1 Sept 1997

Fernández-Viña M A, Lázaro A M, Marcos C Y, Nulf C, Raimondi E, Haas E J, Stastny P

Abstract excerpt

Native American populations have a limited HLA polymorphism compared with other ethnic groups. In spite of this, many novel HLA-B locus alleles, not observed in other populations, have been identified in South American tribes, and rapid evolution of this locus has been suggested. We have studied unrelated subjects of the Toba (TOB n = 116), Wichi (WIC n = 46) and Pilaga (PIL n = 14) tribes from northeastern...

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PMID: 9331946
DOI: 10.1111/j.1399-0039.1997.tb02867.x

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