Article
Polymorphism at codons 114, 116, 145, and 163 muddle the typing of HLA-B*1304.
Human immunology - 1 Jun 1997
Ellexson M, Lai-Kwan P, Lau M, Muto K, Terasaki P, Cole J, Thompson C, Hildebrand W
Abstract excerpt
Genetic exchanges often muddle the typing of HLA class I molecules, this is also the case for HLA-B*1304. Serologic and molecular DNA class I typing report a B15/B55 type for cell 847, whereas DNA sequencing finds B*5501/B*1304. HLA-B*1304 differs by no more than four amino acids from other HLA-B13 molecules, a comparative analysis of the B13 and B15 families was therefore performed to determine why serologic and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.