Article
Novel HLA-B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types.
Tissue antigens - 1 Mar 1996
Hurley C K, Steiner N, Hoyer R J, Menchaca E, Mitton W, Simonis T, Hartzman R J, Johnson A H, Ng J
Abstract excerpt
Three class I alleles, B*8201, B*3515 and B*5106, have been described using DNA and cDNA sequencing. The B*8201 allele is most structurally related to B*5602, differing from it by 14 nucleotide substitutions resulting in 5 amino acid differences. The other two alleles, B*3515 and B*5106, differ from their most closely related HLA-B alleles by 2-3 nucleotide substitutions resulting in 1-2 amino acid substitutions,...
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