Article
Novel HLA-B alleles, B*8201, B*3515 and B*5106, add to the complexity of serologic identification of HLA types.
Tissue antigens - 1 Mar 1996
Hurley C K, Steiner N, Hoyer R J, Menchaca E, Mitton W, Simonis T, Hartzman R J, Johnson A H, Ng J
Abstract excerpt
Three class I alleles, B*8201, B*3515 and B*5106, have been described using DNA and cDNA sequencing. The B*8201 allele is most structurally related to B*5602, differing from it by 14 nucleotide substitutions resulting in 5 amino acid differences. The other two alleles, B*3515 and B*5106, differ f...
Topics
- Alleles
- Antigenic Variation
- Base Sequence
- HLA-B Antigens
- HLA-B35 Antigen
- HLA-B51 Antigen
- HLA-B8 Antigen
- Humans
- Molecular Sequence Data
- Sequence Homology, Nucleic Acid
