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Article

HLA-DRB1 leprogenic motifs in nigerian population groups.

Clinical and experimental immunology - 1 Oct 1999

Uko G P, Lu L Y, Asuquo M A, Fici D, Mahan S, Awdeh Z, Udim E R, Ding W, Umana U, Adewole T, Fraser P A

Abstract excerpt

Amino acid residues involved in the peptide binding groove of HLA-DRB1 alleles were examined in three Nigerian ethnic groups with leprosy (n = 287) and 170 controls to determine the role of DRB1 alleles in disease outcome with Mycobacterium leprae. Nine positively charged motifs and two others with neutral charge to the binding groove were detected. These motifs occurred more frequently in leprosy (leprogenic)...

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Identifiers

PMID: 10540160
DOI: 10.1046/j.1365-2249.1999.01034.x
PMCID: PMC1905405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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