Article
The role of virologic and immunologic factors in mother-to-child transmission of HIV-1.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Sept 1997
Colognesi C, Halapi E, Jansson M, Hodara V, Steuer G, Tresoldi E, Leitner T, Scarlatti G
Abstract excerpt
PROBLEM: More than 90% of human immunodeficiency virus type 1 (HIV-1) infection in children is acquired by mother-to-child transmission. However, infection of the child occurs in between 14 and 35% of cases. METHOD OF STUDY: To understand the mechanisms involved in HIV-1 transmission, we have inv...
Topics
- Antigenic Variation
- Cytopathogenic Effect, Viral
- Female
- HIV Antibodies
- HIV Antigens
- HIV Infections
- HIV-1
- Humans
- Infant, Newborn
- Infectious Disease Transmission, Vertical
- Maternal-Fetal Exchange
- Neutralization Tests
- Phenotype
- Pregnancy
- Pregnancy Complications, Infectious
- Risk Factors
- Virus Replication