Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Proopiomelanocortin Neurons Are Direct Targets for Leptin in the Hypothalamus

1 Oct 1997

Abstract excerpt

Leptin is a protein product of the obese (ob) gene, which is secreted by adipocytes and functions as a satiety factor to regulate food intake. The expression of the leptin receptor in several hypothalamic nuclei suggests that multiple neuronal subtypes are targets for leptin's action. Products of the proopiomelanocortin (POMC) gene are known to affect feeding behavior, and POMC neurons share a similar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Biochemical Analysis and Sensing Techniques
Share to Regulation of Appetite and Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9322969
DOI: 10.1210/endo.138.10.5570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Proopiomelanocortin Neurons Are Direct Targets for Leptin in the HypothalamusPMID 9322969Read ↗

Regulation of Hypothalamic Proopiomelanocortin mRNA by Leptin in ob/ob MiceSemantic proximity Read ↗

Regulation of Hypothalamic Proopiomelanocortin mRNA by Leptin in ob/ob MiceSemantic proximity Read ↗

Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesitySemantic proximity Read ↗

Leptin Signaling in the Central Nervous System and the PeripherySemantic proximity Read ↗

Neuropeptides and obesity.Semantic proximity Read ↗

Leptin and melanocortin signaling in the hypothalamus.Semantic proximity Read ↗

Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasisSemantic proximity Read ↗

Pro-opiomelanocortin (POMC) Deficiency and Peripheral Melanocortins in ObesitySemantic proximity Read ↗

LRb signals act within a distributed network of leptin-responsive neurones to mediate leptin action.Semantic proximity Read ↗

[The role of leptin and its peptide mediators in neurophysiology].Semantic proximity Read ↗

The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus.Semantic proximity Read ↗

Hypothalamic proopiomelanocortin (POMC) neurons have a cholinergic phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.