Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects.

Molecular psychiatry - 1 May 1997

Kotler M, Cohen H, Segman R, Gritsenko I, Nemanov L, Lerer B, Kramer I, Zer-Zion M, Kletz I, Ebstein R P

Abstract excerpt

Only in the past decade has a role of heredity in substance abuse been established as a result of extensive twin and family studies. More recently, several candidate genes have been investigated for their possible role in alcoholism and cocaine abuse. Specific genetic factors in opioid substance abuse have not been investigated in man, although animal studies suggest that quantitative trait loci (QTLs) can be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Exons
Share to Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Dopamine D2

Share to Receptors, Dopamine D4

Share to Substance-Related Disorders

Source

Identifiers

PMID: 9152990
DOI: 10.1038/sj.mp.4000248

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects.PMID 9152990Read ↗

Association analysis of the dopamine D4 gene exon III VNTR and heroin abuse in Chinese subjects.Semantic proximity Read ↗

The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking.Semantic proximity Read ↗

Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics.Semantic proximity Read ↗

Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene.Semantic proximity Read ↗

Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking.Semantic proximity Read ↗

Additional evidence for an association between the dopamine D4 receptor (D4DR) exon III repeat polymorphism and the human personality trait of Novelty Seeking.Semantic proximity Read ↗

Dopamine D4 receptor gene and personality dimensions in Brazilian male alcoholics.Semantic proximity Read ↗

D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects.Semantic proximity Read ↗

Studies of the 48 bp repeat polymorphism of the DRD4 gene in impulsive, compulsive, addictive behaviors: Tourette syndrome, ADHD, pathological gambling, and substance abuse.Semantic proximity Read ↗

Association of a duplicated repeat polymorphism in the 5'-untranslated region of the DRD4 gene with novelty seeking.Semantic proximity Read ↗

Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: results from a high-risk community sample.Semantic proximity Read ↗

Novelty seeking and the dopamine D4 receptor gene (DRD4) revisited in Asians: haplotype characterization and relevance of the 2-repeat allele.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.