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Article

The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking.

Molecular psychiatry - 1 Nov 1996

Malhotra A K, Virkkunen M, Rooney W, Eggert M, Linnoila M, Goldman D

Abstract excerpt

Ebstein and colleagues have recently reported a significant association between the 7-repeat allele of the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and the personality trait of Novelty Seeking (NS) in 124 Israeli subjects. This study, and another study conducted in the US (although with a different personality measure) that observed a similar association, have generated wide interest in the...

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PMID: 9154232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

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The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking.PMID 9154232Read ↗

Additional evidence for an association between the dopamine D4 receptor (D4DR) exon III repeat polymorphism and the human personality trait of Novelty Seeking.Semantic proximity Read ↗

Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking.Semantic proximity Read ↗

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Association of a duplicated repeat polymorphism in the 5'-untranslated region of the DRD4 gene with novelty seeking.Semantic proximity Read ↗

Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects.Semantic proximity Read ↗

No association between novelty seeking and dopamine D4 receptor (D4DR) exon III seven repeat alleles in Baltimore Longitudinal Study of Aging participants.Semantic proximity Read ↗

Non-association of dopamine D4 and D2 receptor genes with personality in healthy individuals.Semantic proximity Read ↗

Association between novelty seeking and the type 4 dopamine receptor gene in a large Finnish cohort sample.Semantic proximity Read ↗

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Novelty seeking and the dopamine D4 receptor gene (DRD4) revisited in Asians: haplotype characterization and relevance of the 2-repeat allele.Semantic proximity Read ↗

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