Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics.

American journal of medical genetics - 19 Sept 1997

Sander T, Harms H, Dufeu P, Kuhn S, Rommelspacher H, Schmidt L G

Abstract excerpt

A dysfunction of dopaminergic neurotansmission has been implicated in alcohol-seeking behavior. Recently, a significant association between the seven-repeat allele (DRD4*7R) of a 16 amino acid motif in the third exon of the dopamine D4 receptor gene (DRD4) and the personality trait of novelty seeking has been reported. Our population-based association study tested the hypothesis that the DRD4*7R variant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Alleles
Share to Exons

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Exploratory Behavior

Share to Polymorphism, Genetic

Share to Receptors, Dopamine D2

Share to Receptors, Dopamine D4

Source

Identifiers

PMID: 9342196
DOI: 10.1002/(sici)1096-8628(19970919)74:5<483::aid-ajmg5>3.0.co;2-p

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics.PMID 9342196Read ↗

Dopamine D4 receptor gene and personality dimensions in Brazilian male alcoholics.Semantic proximity Read ↗

The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking.Semantic proximity Read ↗

D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects.Semantic proximity Read ↗

Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects.Semantic proximity Read ↗

Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking.Semantic proximity Read ↗

No association between novelty seeking and dopamine D4 receptor (D4DR) exon III seven repeat alleles in Baltimore Longitudinal Study of Aging participants.Semantic proximity Read ↗

Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene.Semantic proximity Read ↗

Non-association of dopamine D4 and D2 receptor genes with personality in healthy individuals.Semantic proximity Read ↗

Additional evidence for an association between the dopamine D4 receptor (D4DR) exon III repeat polymorphism and the human personality trait of Novelty Seeking.Semantic proximity Read ↗

Association study between dopamine D3 receptor gene variant and personality traits.Semantic proximity Read ↗

[Association studies of dopamine D4 receptor gene exon 3 in patients with alcohol dependence].Semantic proximity Read ↗

Association of a duplicated repeat polymorphism in the 5'-untranslated region of the DRD4 gene with novelty seeking.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.