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Article

Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics.

American journal of medical genetics - 19 Sept 1997

Sander T, Harms H, Dufeu P, Kuhn S, Rommelspacher H, Schmidt L G

Abstract excerpt

A dysfunction of dopaminergic neurotansmission has been implicated in alcohol-seeking behavior. Recently, a significant association between the seven-repeat allele (DRD4*7R) of a 16 amino acid motif in the third exon of the dopamine D4 receptor gene (DRD4) and the personality trait of novelty see...

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Alcoholism
Alleles
Exons
Exploratory Behavior
Polymorphism, Genetic
Receptors, Dopamine D2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Dopamine D4

Source

Identifiers

PMID: 9342196
DOI: 10.1002/(sici)1096-8628(19970919)74:5<483::aid-ajmg5>3.0.co;2-p

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-9342196-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics.PMID 9342196Read ↗

Dopamine D4 receptor gene and personality dimensions in Brazilian male alcoholics.Semantic proximity Read ↗

The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking.Semantic proximity Read ↗

D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects.Semantic proximity Read ↗

Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects.Semantic proximity Read ↗

Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking.Semantic proximity Read ↗

No association between novelty seeking and dopamine D4 receptor (D4DR) exon III seven repeat alleles in Baltimore Longitudinal Study of Aging participants.Semantic proximity Read ↗

Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene.Semantic proximity Read ↗

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Additional evidence for an association between the dopamine D4 receptor (D4DR) exon III repeat polymorphism and the human personality trait of Novelty Seeking.Semantic proximity Read ↗

Association study between dopamine D3 receptor gene variant and personality traits.Semantic proximity Read ↗

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Association of a duplicated repeat polymorphism in the 5'-untranslated region of the DRD4 gene with novelty seeking.Semantic proximity Read ↗

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