Article
HLA-B*1559: a hybrid allele including exon 2 of HLA-B35 and exon 3 of HLA-B15 and serologically typed as B35.
Tissue antigens - 1 Nov 2000
Magira E, Beznik-Cizman B, Monos D
Abstract excerpt
The new allele HLA-B*1559 described is of Hispanic origin. This allele carries the exon 2 of HLA-B*35 alleles, and is identical to HLA-B*3501 and the exon 3 of HLA-B*1530. Serologically it is typed as B35. The most likely scenario for its generation seems to be a gene conversion event that involved the, frequent in Hispanic populations, B*1522 allele and a B*1530 allele. A segment of the B*1530 allele that...
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