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Article

Binding of the Complement Inhibitor C4bp to Serogroup B Neisseria meningitidis

1 May 2005

Abstract excerpt

Neisseria meningitidis (meningococcus) is an important cause of meningitis and sepsis. Currently, there is no effective vaccine against serogroup B meningococcal infection. Host defense against neisseriae requires the complement system (C) as indicated by the fact that individuals deficient in properdin or late C components (C6-9) have an increased susceptibility to recurrent neisserial infections. Because the...

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PMID: 15879129
DOI: 10.4049/jimmunol.174.10.6299

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