Article
Ontogeny of the immune system: gamma/delta and alpha/beta T cells migrate from thymus to the periphery in alternating waves.
The Journal of experimental medicine - 6 Oct 1997
Dunon D, Courtois D, Vainio O, Six A, Chen C H, Cooper M D, Dangy J P, Imhof B A
Abstract excerpt
The embryonic thymus is colonized by the influx of hemopoietic progenitors in waves. To characterize the T cell progeny of the initial colonization waves, we used intravenous adoptive transfer of bone marrow progenitors into congenic embryos. The experiments were performed in birds because intrav...
Topics
- Adoptive Transfer
- Amino Acid Sequence
- Animals
- Bone Marrow Cells
- Cell Differentiation
- Cell Movement
- Chick Embryo
- Cloning, Molecular
- DNA Primers
- Gene Rearrangement, T-Lymphocyte
- Hematopoietic Stem Cells