Article
Ontogeny of the immune system: gamma/delta and alpha/beta T cells migrate from thymus to the periphery in alternating waves.
The Journal of experimental medicine - 6 Oct 1997
Dunon D, Courtois D, Vainio O, Six A, Chen C H, Cooper M D, Dangy J P, Imhof B A
Abstract excerpt
The embryonic thymus is colonized by the influx of hemopoietic progenitors in waves. To characterize the T cell progeny of the initial colonization waves, we used intravenous adoptive transfer of bone marrow progenitors into congenic embryos. The experiments were performed in birds because intravenous cell infusions can be performed more efficiently in avian than in mammalian embryos. Progenitor cells, which...
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