A population of early fetal thymocytes expressing Fc gamma RII/III contains precursors of T lymphocytes and natural killer cells.

doi:10.1016/0092-8674(92)90125-v

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Article

A population of early fetal thymocytes expressing Fc gamma RII/III contains precursors of T lymphocytes and natural killer cells.

Cell - 3 Apr 1992

Rodewald H R, Moingeon P, Lucich J L, Dosiou C, Lopez P, Reinherz E L

Abstract excerpt

We have identified a dominant fetal thymocyte population at day 14.5 of gestation in the mouse that lacks CD4 and CD8 but expresses Fc gamma RII/III several days prior to acquisition of the T cell receptor (TCR) in vivo. If maintained in a thymic microenvironment, this population of CD4-CD8-TCR-Fc gamma RII/III+ thymocytes differentiates first into CD4+CD8+TCRlowFc gamma RII/III- thymocytes and subsequently...

Topics

Animals
Antigens, CD
Antigens, Differentiation
Base Sequence
Cell Differentiation
Cytotoxicity Tests, Immunologic
Fetus
Flow Cytometry
Killer Cells, Natural
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Phenotype

Polymerase Chain Reaction

Receptors, Fc

Receptors, IgG

T-Lymphocytes

Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 1532536
DOI: 10.1016/0092-8674(92)90125-v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1532536-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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