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Controversy surrounding the increased expression of TGFβ1 in asthma

24 Sept 2007

Abstract excerpt

Asthma is a waxing and waning disease that leads to structural changes in the airways, such as subepithelial fibrosis, increased mass of airway smooth muscle and epithelial metaplasia. Such a remodeling of the airways further amplifies asthma symptoms, but its etiology is unknown. Transforming growth factor beta1 is a pleiotropic cytokine involved in many fibrotic, oncologic and immunologic diseases and is...

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PMID: 17892594
DOI: 10.1186/1465-9921-8-66

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