Article
Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.
The Annals of thoracic surgery - 1 Sept 1997
Tardiff B E, Newman M F, Saunders A M, Strittmatter W J, Blumenthal J A, White W D, Croughwell N D, Davis R D, Roses A D, Reves J G
Abstract excerpt
BACKGROUND: Changes in memory and cognition frequently follow cardiac operations. We hypothesized that patients with the apolipoprotein E-epsilon 4 allele are genetically predisposed to cognitive dysfunction after cardiac operations. METHODS: The apolipoprotein E-epsilon 4 allele was evaluated as a predictor variable for postoperative cognitive dysfunction in 65 patients undergoing cardiac bypass grafting at Duke...
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