Cloning of a Novel Transcription Factor-Like Gene Amplified in Human Glioma Including Astrocytoma Grade I

Abstract excerpt

Gene amplification, which is generally considered to occur late in tumor development, is a common feature of high grade glioma. Up until now, there have been no reports on amplification in astrocytoma grade I. In this study, we report cloning and sequencing of a cDNA termed glioma-amplified sequence (GAS41) which was identified recently in a glioblastoma cell line by microdissection-mediated cDNA capture. This...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Glioma Diagnosis and Treatment
• Share to Microtubule and mitosis dynamics
• Share to RNA Research and Splicing